class switch Archives

IgA – Faster, Stronger and More Effective.

11 March 2021

The Star Player On Your Team. Following seroconversion, immumoglobulin A (IgA) istoype is the most frequently created antibody in the immune system. This is principally because it dominates the upper respiratory tract, which is usually the first point of contact between pathogen and human. Therefore, it is needed more frequently than the other isotypes. As […]

Exoribonuclease – Your Starter For Ten Mr Prime Minister.

30 December 2020

Q1. How can a virus containing an exoribonuclease mutate in the way you are saying? Coronaviruses possess an exoribonuclease within nonstructural protein 14 (nsp14-ExoN). This functions as a proofreader during viral transcription and encoding, ensuring high fidelity replication. This minimises the potential for mutation, as shown by the fact that sarbecovirus/lineage B betacoronaviruses with their […]