IgA – Faster, Stronger and More Effective.

The Star Player On Your Team. Following seroconversion, immumoglobulin A (IgA) istoype is the most frequently created antibody in the immune system. This is principally because it dominates the upper respiratory tract, which is usually the first point of contact between pathogen and human. Therefore, it is needed more frequently than the other isotypes. As […]

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Why Geographical Naming Of Variants Is Wrong.

B1.1.28 and B1.351 – They Are All ‘Johnny Foreigner’ Variants To The Government. In recent months, the government has made much of the emergence of new ‘killer mutations of death’, obsessing about ‘South African’ and ‘Brazilian’ geographical variants. Before going further, one should refer to these variants by their correct designations: the Brazilian variant is […]

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More Infectious Equals More Vulnerable.

Infectiousness And Infectivity Are Not The Same. Infectiousness is how easily a pathogen can spread and infectivity is the level of disease severity it can cause. We explained this in more detail earlier this month in response to the UK government’s regular – and one would predicate deliberate – confusion of the two. S-VoC / […]

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Nitric Oxide Immunity In The Upper Respiratory Tract.

The Upper Respiratory Tract Is The Key Battleground. Back in July 2020, we first explained the crucial significance of vitamin D as an effective viral countermeasure as well as the significance of vitamin D deficiency in SARS-CoV-2’s pathogenesis and COVID-19 disease severity. Then in October we highlighted the importance of the vitamin D→endothelial nitric oxide synthase→nitric […]

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WHO Shows PCR Testing Gets It Wrong.

What Is Nucleic Acid Testing? Nucleic acid testing, more commonly known as PCR or RT-PCR testing, is one of the three main types of viral testing. There is a full explanation of these three types here but concentrating on PCR testing, it tests a sample for tiny fragments of viral RNA. It shows only the […]

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Antibody-Dependent Enhancement And This Rushed ‘Vaccine’.

What is Antibody-Dependent Enhancement? As we have set out previously, it takes 10-15 years to develop a vaccine. This timescale is entirely understandable and justifiable when you consider that the vaccine has to be both effective and safe. Safe includes not causing unacceptable side effects, which include the vaccine or immune system’s response triggering autoimmunity, […]

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Exoribonuclease – Your Starter For Ten Mr Prime Minister.

Q1. How can a virus containing an exoribonuclease mutate in the way you are saying? Coronaviruses possess an exoribonuclease within nonstructural protein 14 (nsp14-ExoN). This functions as a proofreader during viral transcription and encoding, ensuring high fidelity replication. This minimises the potential for mutation, as shown by the fact that sarbecovirus/lineage B betacoronaviruses with their […]

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