Antiphospholipid Antibodies And COVID-19 Vaccines.

Background. As early as October 2020 – over ten months ago – we explained why a vaccine was not needed and would not be effective. That’s a vaccine using its correct medical definition, i.e. a prophylactic treatment providing long-term or lifetime protection. All of the four main treatment candidates being injected – Vaxzevria; BNT126b2; mRNA-1273 […]

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The ‘Third Wave’ That Has Been Here All Along.

B1.1.7 v B1.1.28 v B1.351. As we have previously explained, SARS-CoV-2 neither thinks nor acts geographically. Yet the misleading designation of SARS-CoV-2 variants on a geographical basis continues to dominate media coverage and government obsession, with the putative ‘third wave’ being down to either the Brazilian variant or the UK variant dependent upon whether you […]

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IgA – Faster, Stronger and More Effective.

The Star Player On Your Team. Following seroconversion, immumoglobulin A (IgA) istoype is the most frequently created antibody in the immune system. This is principally because it dominates the upper respiratory tract, which is usually the first point of contact between pathogen and human. Therefore, it is needed more frequently than the other isotypes. As […]

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Exoribonuclease – Your Starter For Ten Mr Prime Minister.

Q1. How can a virus containing an exoribonuclease mutate in the way you are saying? Coronaviruses possess an exoribonuclease within nonstructural protein 14 (nsp14-ExoN). This functions as a proofreader during viral transcription and encoding, ensuring high fidelity replication. This minimises the potential for mutation, as shown by the fact that sarbecovirus/lineage B betacoronaviruses with their […]

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Having A Common Cold Is As Good As A Vaccine.

Learn From The Common Cold. Pretty much everybody now knows that four coronaviruses cause the common cold: duvinacovirus alphacoronavirus HCoV-229E & setracovirus alphacoronavirus HCoV-NL63 and embecovirus or lineage A betacoronaviruses HCoV-HKU1 and HCoV-OC43. That’s the common cold that you can catch over & over and which is dealt with by the innate immune system only, […]

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Déjà vu – memory T cells have seen SARS-CoV-2 before.

Newly-Discovered Is Not New. In early September we first highlighted the incorrect designation of SARS-CoV-2 as a ‘novel’ or ‘new’ coronavirus when it should have been designated ‘newly-discovered’. There is a subtle but fundamental difference: something that is new did not previously exist whereas something that is newly-discovered already existed but not been discovered yet. […]

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