What Makes SARS-CoV-2 More Infectious.

The Role Of The RBM:ACE2 Interface. A little over a year ago, we set out how increased infectiousness meant greater vulnerability, i.e. a new variant may be more infectious but it is also more susceptible to destruction by the innate immune response. The chances are that most people now know what a structural spike protein […]

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How Each Of Us Causes Every Variant.

The Four Nucleobases. Almost exactly twelve months ago, we explained how increased transmissibility also meant greater vulnerability, i.e. a new variant may be more infectious but it is also more susceptible to detection by the immune system. This was first evidenced by our study of SARS-CoV-2-SG614, also one year ago now. Despite there being virtually […]

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Yet Another Virus That Provides SARS-CoV-2 Immunity.

Background. It is difficult to select the most fundamental error relating to SARS-CoV-2: the deliberate confusion of ‘infectiousness’ with ‘infectivity’; the deliberate use of ‘COVID-19’ disease severity when one is referring to ‘SARS-CoV-2’ viral infection, for example ‘rising COVID-19 infections’ when there is no such thing; the use of ‘vaccination’ when the correct description is […]

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How Low Is The SARS-CoV-2 Mortality Rate?

We All Grew Up With Coronaviruses, As Did All Our Ancestors. To understand the relevance of mortality rate, you have to appreciate that coronaviruses first became pathogenic to humans in the range 12,000 – 10,000 years ago, as a consequence of the first interaction between humans and livestock that occurred in the early Holocene. Mankind […]

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Why Delta / B1.617.2 Is NOT A Problem.

Just What Is Different About Delta? B1.617.2/Delta is apparently still spreading.  This is unsurprising given that it has been occurring globally for over eight months. At least the WHO has finally applied a nomenclature to the main SARS-CoV-2 variants, adding to the existing PANGO and Nextstrain designations.  This validates something we first highlighted four months […]

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Why SARS-CoV-2 Is NOT Airborne Spread.

‘The Ships Hung In The Sky In Much The Same Way That Bricks Don’t.’ The above is a line from Douglas Adams’ The Hitchhiker’s Guide To The Galaxy, referring to the arrival of the Vogon Constructor Fleet. The relevance to SARS-CoV-2 is that even a brick if thrown is airborne spread…for a very short time. It […]

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Tests That Would Have Saved Thousands.

UK COVID-19 mortality rate remains one of the highest in the world. On a population-adjusted basis (for fair comparison) the UK mortality rate is 4.36x the worldwide average, which means there have been an additional 98,364 deaths in the UK (@0500UTC 13/05/21, source: Johns Hopkins Coronavirus Resource Center/Worldmeters). Deaths that were avoidable. One of the […]

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The ‘Third Wave’ That Has Been Here All Along.

B1.1.7 v B1.1.28 v B1.351. As we have previously explained, SARS-CoV-2 neither thinks nor acts geographically. Yet the misleading designation of SARS-CoV-2 variants on a geographical basis continues to dominate media coverage and government obsession, with the putative ‘third wave’ being down to either the Brazilian variant or the UK variant dependent upon whether you […]

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