innate immune Archives

These Are Not The Drugs You Are Looking For.

20 November 2020

Don’t Use Remdesivir. Just one month after the US Food and Drug Administration approved remdesivir as an antiviral for the treatment of patients with COVID-19, the WHO yesterday recommended that it not be used, on the basis that it is ineffective and there is “no evidence” it reduces mortality. Last month, we analysed remdesivir’s use […]

Monetising A Vaccine Shows What It’s Really All About.

7 November 2020

LOADSAMONEY! According to the sales pitch on Thursday from investment banks Credit Suisse and Morgan Stanley, a COVID-19 vaccine could be a “bumper revenue opportunity“, projected to earn at least $10 billion a year. Morgan Stanley’s projection is at least $10 billion a year across developed countries but Credit Suisse is bigging it up further […]

An antiviral maybe but a vaccine isn’t needed and wouldn’t be effective.

20 October 2020

Apparently everything now hangs on a vaccine: stockmarkets rise and fall on the mere rumour of how the rumoured development of a particular rumoured COVID-19 vaccine is going; politicians say that normality can’t be resumed until a vaccine is available; people are fed the line that a virus must have a vaccine and that without […]

Fever is cool. It is the body’s normal response to an infection and is certainly NOT unique to SARS-CoV-2.

16 October 2020

Core temperature Fever – or to use its medical term ‘pyrexia’ – is defined as an increase in the body’s core temperature. The body’s core temperature is 37’c, give or take, although various studies have shown that it can be anywhere in the range 36’c – 38’c and as a consequence 36.5’c – 37.5’c is […]

Vitamin D, eNOS and NO – your partners in fighting SARS-CoV-2

3 October 2020

An Achilles heel Following on from our first article last month on key reasons why the UK government strategy & response have been so wrong and caused the deaths of tens of thousands of people, this article outlines the key roles of vitamin D, endothelial nitric oxide synthase (eNOS or NOS3) and nitric oxide in […]

Your immune system: ‘Make pumps four, person reported.’

3 May 2020

If you are old enough to remember London’s Burning (if not, it’s still shown on the Drama channel) you will recall that each programme would build toward the main event – a fire that was the culmination of every episode. Despite the show being about a single theme – fire – you never knew just […]

Why is Europe now doing even worse?

8 April 2020

Analysing the latest figures from Johns Hopkins Coronavirus Resource Center, the worldwide average for deaths per 1million population is now 10.5, which is 0.00105%. Compare this to the worldwide average death rate for seasonal or winter flu of 0.1% (source: World Health Organisation). The COVID-19 death rate is currently 95x lower than seasonal or winter […]

Understand viral dose and viral load. The government response has turned NHS frontline staff into viral suicide bombers.

6 April 2020

A lot of current medical discussion revolves around viral load, which is the amount of virus within an infected person’s body. This can determine the severity of symptoms if they develop the disease as well as their level of viral shedding, i.e. the amount of virus in their excreta (for SARS-CoV-2, their mucus). Those with […]