nsp3 Archives

Nitric Oxide’s Role In Anti-Adhesion And Anti-Coagulation.

13 December 2021

Background. SARS-CoV-2’s Achilles’ heel has always been vitamin D in general and nitric oxide in particular. We first explained the relevance of vitamin D in July 2020, identifying the correlation between vitamin D deficiency and COVID-19 mortality rates and the key role of exposure to photosynthesis of vitamin D from exposure to UVB that occurs […]

Cathelicidin – Another Key Benefit Of Vitamin D.

29 October 2021

Background. It is impossible to ignore the pivotal role of vitamin D both in preventing SARS-CoV-2 viral infection (through the eNOS→nitric oxide pathway) and in reducing COVID-19 disease severity (through the cholecalciferol→ calcifediol→calcitriol pathway). As early as July 2020 we had identified the positive correlation between COVID-19 mortality rate and vitamin D deficiency. By October […]

Why Is Nitric Oxide’s Key Role Ignored?

28 July 2021

Role In The Innate Immune Response. It is a year since we first identified the significance of vitamin D in respect of SARS-CoV-2. Through the vitamin D pathways it can both prevent viral infection and attenuate disease progression and severity. Yet the role of vitamin D-modulated nitric oxide remains largely ignored and dismissed by the NHS as […]

SARS-COV-2’s Defences Against Detection.

18 May 2021

What Variants Want. Considerable coverage is being given to variant B1.617. This is the ‘Indian’ variant if you use the incorrect basis of giving single country, geographical names to variants that appear globally across multiple variants and are not new, having been in existence for months and in some cases, over a year. As part […]

Is Ivermectin Another ‘Wonderdrug’?

21 April 2021

Is This Remdesivirmania Redux? Ivermectin is the subject of increasing coverage and concomitant hysteria around it being another ‘wonderdrug’ for the treatment of SARS-CoV-2. It has been touted as a potential treatment since the days of remdesivir, chloroquine, hydroxychloroquine and lopinavir. We picked apart remdesivir in October 2020, days after it was approved by the […]

Rhinoviruses Increase SARS-CoV-2 Immunity.

31 March 2021

Persistent Antigen Exposure. We first highlighted persistent antigen exposure back in November 2020, when our research showed that individuals who had not previously had SARS-CoV-2 possessed memory T cells that recognised it, with this recognition likely coming from previous exposure to other common cold-causing coronaviruses. Public Health England that commissioned the report stated (with our […]

Nitric Oxide Immunity In The Upper Respiratory Tract.

24 January 2021

The Upper Respiratory Tract Is The Key Battleground. Back in July 2020, we first explained the crucial significance of vitamin D as an effective viral countermeasure as well as the significance of vitamin D deficiency in SARS-CoV-2’s pathogenesis and COVID-19 disease severity. Then in October we highlighted the importance of the vitamin D→endothelial nitric oxide synthase→nitric […]

Vitamin D, eNOS and NO – your partners in fighting SARS-CoV-2

3 October 2020

An Achilles heel Following on from our first article last month on key reasons why the UK government strategy & response have been so wrong and caused the deaths of tens of thousands of people, this article outlines the key roles of vitamin D, endothelial nitric oxide synthase (eNOS or NOS3) and nitric oxide in […]