pp1ab Archives

Nitric Oxide’s Role In Anti-Adhesion And Anti-Coagulation.

13 December 2021

Background. SARS-CoV-2’s Achilles’ heel has always been vitamin D in general and nitric oxide in particular. We first explained the relevance of vitamin D in July 2020, identifying the correlation between vitamin D deficiency and COVID-19 mortality rates and the key role of exposure to photosynthesis of vitamin D from exposure to UVB that occurs […]

Cathelicidin – Another Key Benefit Of Vitamin D.

29 October 2021

Background. It is impossible to ignore the pivotal role of vitamin D both in preventing SARS-CoV-2 viral infection (through the eNOS→nitric oxide pathway) and in reducing COVID-19 disease severity (through the cholecalciferol→ calcifediol→calcitriol pathway). As early as July 2020 we had identified the positive correlation between COVID-19 mortality rate and vitamin D deficiency. By October […]

Is Ivermectin Another ‘Wonderdrug’?

21 April 2021

Is This Remdesivirmania Redux? Ivermectin is the subject of increasing coverage and concomitant hysteria around it being another ‘wonderdrug’ for the treatment of SARS-CoV-2. It has been touted as a potential treatment since the days of remdesivir, chloroquine, hydroxychloroquine and lopinavir. We picked apart remdesivir in October 2020, days after it was approved by the […]

Why The S Protein Is Not The Target You Are Looking For.

11 February 2021

The First Lesson Of Camouflage – Not Being Seen. The majority of vaccines and antivirals both in use and in development as SARS-CoV-2 countermeasures target the structural Spike protein. We have highlighted previously that as the S protein trimers contain the RBDs, the S protein houses the virion’s principal weapon and is therefore the obvious, […]

These Are Not The Drugs You Are Looking For.

20 November 2020

Don’t Use Remdesivir. Just one month after the US Food and Drug Administration approved remdesivir as an antiviral for the treatment of patients with COVID-19, the WHO yesterday recommended that it not be used, on the basis that it is ineffective and there is “no evidence” it reduces mortality. Last month, we analysed remdesivir’s use […]