What Makes SARS-CoV-2 More Infectious.

The Role Of The RBM:ACE2 Interface. A little over a year ago, we set out how increased infectiousness meant greater vulnerability, i.e. a new variant may be more infectious but it is also more susceptible to destruction by the innate immune response. The chances are that most people now know what a structural spike protein […]

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Why Delta / B1.617.2 Is NOT A Problem.

Just What Is Different About Delta? B1.617.2/Delta is apparently still spreading.  This is unsurprising given that it has been occurring globally for over eight months. At least the WHO has finally applied a nomenclature to the main SARS-CoV-2 variants, adding to the existing PANGO and Nextstrain designations.  This validates something we first highlighted four months […]

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The ‘Third Wave’ That Has Been Here All Along.

B1.1.7 v B1.1.28 v B1.351. As we have previously explained, SARS-CoV-2 neither thinks nor acts geographically. Yet the misleading designation of SARS-CoV-2 variants on a geographical basis continues to dominate media coverage and government obsession, with the putative ‘third wave’ being down to either the Brazilian variant or the UK variant dependent upon whether you […]

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Clap For Chris – The Greatest Scientist…NOT.

This Man Is Supposed To Be In Charge. Earlier this week, the Chief Medical Officer was heckled in the street by someone who disagreed with him. Perhaps not the most appropriate way to make your point – even if the point being made was absolutely correct – but if you are a true leader and […]

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These Are Not The Drugs You Are Looking For.

Don’t Use Remdesivir. Just one month after the US Food and Drug Administration approved remdesivir as an antiviral for the treatment of patients with COVID-19, the WHO yesterday recommended that it not be used, on the basis that it is ineffective and there is “no evidence” it reduces mortality. Last month, we analysed remdesivir’s use […]

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An antiviral maybe but a vaccine isn’t needed and wouldn’t be effective.

Apparently everything now hangs on a vaccine: stockmarkets rise and fall on the mere rumour of how the rumoured development of a particular rumoured COVID-19 vaccine is going; politicians say that normality can’t be resumed until a vaccine is available; people are fed the line that a virus must have a vaccine and that without […]

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