S1 Archives

What Makes SARS-CoV-2 More Infectious.

12 February 2022

The Role Of The RBM:ACE2 Interface. A little over a year ago, we set out how increased infectiousness meant greater vulnerability, i.e. a new variant may be more infectious but it is also more susceptible to destruction by the innate immune response. The chances are that most people now know what a structural spike protein […]

Why Delta / B1.617.2 Is NOT A Problem.

6 July 2021

Just What Is Different About Delta? B1.617.2/Delta is apparently still spreading. This is unsurprising given that it has been occurring globally for over eight months. At least the WHO has finally applied a nomenclature to the main SARS-CoV-2 variants, adding to the existing PANGO and Nextstrain designations. This validates something we first highlighted four months […]

The ‘Third Wave’ That Has Been Here All Along.

24 March 2021

B1.1.7 v B1.1.28 v B1.351. As we have previously explained, SARS-CoV-2 neither thinks nor acts geographically. Yet the misleading designation of SARS-CoV-2 variants on a geographical basis continues to dominate media coverage and government obsession, with the putative ‘third wave’ being down to either the Brazilian variant or the UK variant dependent upon whether you […]