sarbecovirus Archives

Exoribonuclease – Your Starter For Ten Mr Prime Minister.

30 December 2020

Q1. How can a virus containing an exoribonuclease mutate in the way you are saying? Coronaviruses possess an exoribonuclease within nonstructural protein 14 (nsp14-ExoN). This functions as a proofreader during viral transcription and encoding, ensuring high fidelity replication. This minimises the potential for mutation, as shown by the fact that sarbecovirus/lineage B betacoronaviruses with their […]

PCR Testing Is Picking Up The Common Cold.

23 December 2020

Mutation = Phylogenetic Evolution. Not content with inventing the most recent ‘killer mutation of death’, there are now apparently even more new strains of the ‘killer virus of death’ (the one that continues to not kill people, especially those it infects). There is now even one supposedly from South Africa (“this is an illegal mutating, […]

Having A Common Cold Is As Good As A Vaccine.

15 December 2020

Learn From The Common Cold. Pretty much everybody now knows that four coronaviruses cause the common cold: duvinacovirus alphacoronavirus HCoV-229E & setracovirus alphacoronavirus HCoV-NL63 and embecovirus or lineage A betacoronaviruses HCoV-HKU1 and HCoV-OC43. That’s the common cold that you can catch over & over and which is dealt with by the innate immune system only, […]

Déjà vu – memory T cells have seen SARS-CoV-2 before.

23 November 2020

Newly-Discovered Is Not New. In early September we first highlighted the incorrect designation of SARS-CoV-2 as a ‘novel’ or ‘new’ coronavirus when it should have been designated ‘newly-discovered’. There is a subtle but fundamental difference: something that is new did not previously exist whereas something that is newly-discovered already existed but not been discovered yet. […]

It is a virus not the virus.

21 March 2020

Most individuals will contract a virus from at least one of the four coronavirus genera many times throughout in their lifetime, with alphacoronaviruses HCoV-229E and HCoV-NL63, and betacoronaviruses HCoV-HKU1 and HCoV-OC43 causing the common cold. Within the fours genera there are at least 23 specific known species of virus and with serotypes and probable species, […]