What Makes SARS-CoV-2 More Infectious.

The Role Of The RBM:ACE2 Interface. A little over a year ago, we set out how increased infectiousness meant greater vulnerability, i.e. a new variant may be more infectious but it is also more susceptible to destruction by the innate immune response. The chances are that most people now know what a structural spike protein […]

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How Each Of Us Causes Every Variant.

The Four Nucleobases. Almost exactly twelve months ago, we explained how increased transmissibility also meant greater vulnerability, i.e. a new variant may be more infectious but it is also more susceptible to detection by the immune system. This was first evidenced by our study of SARS-CoV-2-SG614, also one year ago now. Despite there being virtually […]

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Tests That Would Have Saved Thousands.

UK COVID-19 mortality rate remains one of the highest in the world. On a population-adjusted basis (for fair comparison) the UK mortality rate is 4.36x the worldwide average, which means there have been an additional 98,364 deaths in the UK (@0500UTC 13/05/21, source: Johns Hopkins Coronavirus Resource Center/Worldmeters). Deaths that were avoidable. One of the […]

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The ‘Third Wave’ That Has Been Here All Along.

B1.1.7 v B1.1.28 v B1.351. As we have previously explained, SARS-CoV-2 neither thinks nor acts geographically. Yet the misleading designation of SARS-CoV-2 variants on a geographical basis continues to dominate media coverage and government obsession, with the putative ‘third wave’ being down to either the Brazilian variant or the UK variant dependent upon whether you […]

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Why Geographical Naming Of Variants Is Wrong.

B1.1.28 and B1.351 – They Are All ‘Johnny Foreigner’ Variants To The Government. In recent months, the government has made much of the emergence of new ‘killer mutations of death’, obsessing about ‘South African’ and ‘Brazilian’ geographical variants. Before going further, one should refer to these variants by their correct designations: the Brazilian variant is […]

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Clap For Chris – The Greatest Scientist…NOT.

This Man Is Supposed To Be In Charge. Earlier this week, the Chief Medical Officer was heckled in the street by someone who disagreed with him. Perhaps not the most appropriate way to make your point – even if the point being made was absolutely correct – but if you are a true leader and […]

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More Infectious Equals More Vulnerable.

Infectiousness And Infectivity Are Not The Same. Infectiousness is how easily a pathogen can spread and infectivity is the level of disease severity it can cause. We explained this in more detail earlier this month in response to the UK government’s regular – and one would predicate deliberate – confusion of the two. S-VoC / […]

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